Introduction Hello everyone, my name is Paras Thakan. I am now pursuing a Master of Pharmacy in the field of Pharmaceutical Analysis. I'd love to talk about the role of medication metabolism. You might be wondering why the topic is CYP450 and I'm talking about drug metabolism. Before discussing the significance of CYP450 microsomal enzymes, it is critical to first understand drug metabolism. What is Drug Metabolism Suppose you have a fever and take paracetamol. Have you ever wondered what happens to a medicine once it enters the body? The answer is simple: when paracetamol enters your body, it diffuses into the bloodstream and reaches your liver. The medicine is active in the liver and becomes inactive because of enzymatic processes before being eliminated in your body via urine. Drug metabolism refers to the process by which a drug transitions from an active to inactive state. Why Drug Metabolism? Certain metabolites produced after medication reactions can induce serious pat...
CYP450 microsomal enzymes may be the hidden players in drug metabolism, but their influence is enormous. Understanding these enzymes not only enhances our grasp of drug interactions but also enables more tailored and effective treatment approaches for patients. As research continues to evolve, the role of CYP450 enzymes will undoubtedly shape the future of pharmacology and personalized medicine.